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molecular formula:c46h58n4o14s
molecular weight:923.0361
cas no.:2068-78-2
appearance: white or almost white crystalline powder
purity(hplc):≥99.0%
quality standard:usp36 ep7.0
packing:20g/bag,50g/bag
storage conditions:protect from light, tightly sealed, freezer storage(less than -20℃).
Descriptions:
vincristine is an extract from catharanthus. the anti-cancer target is canaliculus, mainly suppressing the polymerization of tubulin to suppress the spindle formation and stop the mitosis at metaphase. it can interfere with protein metabolism and suppress activeness of rna. it can suppress the synthesis of cell membrane lipid and transferring of amino acid on cell membrane. vincristine has stronger effect to suppress the transplantation of cancer than catharanthine.
main function of vincristine sulfate
by affecting the formation of spindle cells, this production can stop the cells in mid-mitosis, and delay m cell cycle . there is also the inhibition of purine, rna and dna synthesis.
application of vincristine sulfate
pharmaceutical raw materials, oncology drug.
Vinblastine sulphate is effective as a single agent, but its therapeutic effect is enhanced when used in combination with other antineoplastic drugs. Vinblastine sulphate has been used in the treatment of Hodgkin's disease (Stages III and IV); Lymphocytic lymphoma (nodular and diffuse, poorly and well differentiated); Histiocytic lymphoma; Advanced stages of mycosis fungoides; Advanced carcinoma of the testis; Kaposi's sarcoma and Letterer-Siwe disease (histocytosis X). Vinblastine sulphate may be used in the treatment of choriocarcinoma resistant to other chemotherapeutic agents; Carcinoma of the breast, unresponsive to appropriate endocrine surgery and hormonal therapy.
contact information:
Whatsapp:86-18873303856
skype：live:d260a58b346fba38
email：majorina.cai@chembj.com
TEL:+86 18873303856
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