Product Description

Product Name: Furosemide
Synonyms: FUROSEMID;FUROSEMIDE;FRUSEMIDE;2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid;4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID
CAS: 54-31-9
MF: C12H11ClN2O5S
MW: 330.74
EINECS: 200-203-6

Purity:98%

MP: 220 °C

Stability: Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.

Appearance:White crystalline powder

Property: Dissolved in acetone, methanol, dimethyl formamide, slightly soluble in ethanol, insoluble in water. Odorless, almost tasteless.

Description

Furosemide augments radionucide renography and renal scintigraphy by stimulating the flow of urine and thereby aiding in the differentiation of mechanical obstruction from nonobstructive dilatation in patients with hydroureteronephrosis. Furosemide is a loop diuretic used in the treatment of congestive heart failure and edema. It has also been used to prevent thoroughbred and standardbred race horses from bleeding through the nose during races

Clinically for the treatment of cardiac edema, renal edema, ascites of cirrhosis of the liver, dysfunction or vascular disorder caused by the surrounding edema, and can make the upper urinary tract calculi. Its diuretic effect fast, powerful, used for other more serious patients of diuretic is invalid.

Function

1. Furosemide is used in the treatment of hypercalcemia.
2. Furosemide is indicated in the treatment of mild to moderate hypertension, usually in combination with other antihypertensive agents, and as adjuncts in the treatment of hypertensive crisis.
3. Furosemide is especially useful in patients refractory to other diuretics or with existing acid-base disorders, congestive heart failure, or renal disease.
4. Furosemide is indicated as adjunct in the treatment of acute pulmonary edema.
5. Furosemide is indicated in the treatment of edema associated with congestive heart failure, hepatic cirrhosis, and renal disease (including nephrotic syndrome). . 

Used as a diuretic. It is a sulfonamide-based high-efficiency diuretic that acts on the medulla of the medullary sputum. It has a strong and short diuretic effect and can increase the excretion of water, sodium, chlorine, potassium, calcium, magnesium and phosphate.
1. Edema: treatment of water caused by congestive heart failure, cirrhosis, and kidney disease
swollen. Furosemide bulk drug high-efficiency diuretic, can be used for other diuretic drugs with poor efficacy and urgent need for diuretic clinical situation. Furosemide bulk drugs can be used in adults, children and infants.
2, high blood pressure: can be used alone or in combination with other drugs. This product may be effective when the thiazide is ineffective. However, it is contraindicated in patients with no urine and those who are allergic to the product
3. Acute pulmonary edema or cerebral edema.
4, with rehydration, accelerate the elimination of some poisons excreted by the kidney

Applications

• Used for the treatment of edema caused by heart, liver, kidney and other diseases.

   

  Furosemide is primarily used for the treatment of hypertension and edema. It is the first-line agent in most people with edema caused by congestive heart failure. It is also used for hepaticcirrhosis, renal impairment, nephrotic syndrome, in adjunct therapy for cerebral or pulmonary edema where rapiddiuresis is required (IV injection), and in the management of severe hypercalcemia in combination with adequate rehydration.

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