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Wuhan Yuancheng Gongchuang Technology Co., Ltd.
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Street Address
No. 426 Zhongshan Road, Wuchang District
Country/Region
China/Hubei
Telephone

86-027-88325765

offer high quality AGOMELATINE CAS NO: 138112-76-2
offer high quality AGOMELATINE CAS NO: 138112-76-2
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China
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Product Description

99.8% agomelatine/agomelatine powder 138112-76-2

 

99.8% agomelatine/agomelatine powder 138112-76-2

 

 

 

 

 

Product Name:  Agomelatine

CAS NO:   138112-76-2

Molecular Formula:   C12H18N4O5S

Formula Weight:  330.3601

Appearance: White crystalline power

Assay: 99.0% Min

 

Agomelatine is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported to not produce discontinuation syndrome and have no sexual side effects compared to SSRIsSNRIs and the older tricyclic antidepressants. Agomelatine may also have positive effects on sleep.

 

Function:

 

Agomelatine is a new antidepressant with selective agonist actions at melatonin receptors and selective antagonist action at serotonin 5HT-2C receptors.

 

It does not affect the uptake of serotonin, noradrenaline or dopamine. 

 

Agomelatine can help regulate your'body clock' (circadian rhythm) with positive benefits on mood and sleepin depression Agomelatine is used in the treatment of depression or to help prevent depression returning, and isonly available with a doctor's prescription. The symptoms of depression vary from one person toanother, but commonly include persistent sadness, loss of interest in favourite activities, feelings of worthlessness, sleep problems, feeling of being slowed down, feelings of anxiety or changes in appetite and weight. Changes in your daily sleep and appetite patterns are examples of disturbances of your body clock that occur commonly indepression.

 

Analysis Test

 Specification

 Description

 white crystalline powder,odorless

 Solubility

 Easily soluble in water, unsoluble in ethanol

PH

6.0~7.5

 Solution clarity and color

 solution should be clear and colorless

 

Related substances

5’CMP 0.3%

Simple impurity

Total other impurity

 Chloride

0.05%

Ammonium

0.05%

Fe

0.01%

 Phosphate

0.1%

 Loss on drying

≤6.0%

 Heavy metals

0.002%

 Arsenide

0.0001%

 Bacterial Endotoxins

0.3EU/mg

Microbial Limit

Conforms

Assay(on dried basis)

≥98.0%




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